自噬相关蛋白9B抗体
规格:1mg/1ml
英文名: ATG9B
别名: APG9 like 2; APG9-like 2; APG9L2; Apgdc2; ATG9 autophagy related 9 homolog B; Atg9b; Autophagy related protein 9B; Autophagy-related protein 9B; eONE; Gm574; Nitric oxide synthase 3 overlapping antise
分子量: 94kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ATG9B
交叉反应:Human, Mouse, Rat, Dog, Pig, Rabbit,
细胞定位:
自噬相关蛋白9B抗体产品介绍:background: This gene functions in the regulation of autophagy, a lysosomal degradation pathway. This gene also functions as an antisense transcript in the posttranscriptional regulation of the endothelial nitric oxide synthase 3 gene, which has 3' overlap with this gene on the opposite strand. Mutations in this gene and disruption of the autophagy process have been associated with multiple cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012] Function: Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Subcellular Location: Cytoplasmic vesicle ?autophagosome membrane;自噬相关蛋白9B抗体 Multi-pass membrane protein. Note: Under amino acid starvation or rapamycin treatment, redistributes from a juxtanuclear clustered pool to a dispersed peripheral cytosolic pool. The starvation-induced redistribution depends on ULK1 and ATG13. Tissue Specificity: Highly expressed in placenta (trophoblast cells) and pituitary gland. Not expressed in vascular endothelial. Similarity: Belongs to the ATG9 family. Database links: Entrez Gene: 285973 Human Entrez Gene: 213948 Mouse Entrez Gene: 499973 Rat Omim: 612205 Human SwissProt: Q674R7 Human SwissProt:自噬相关蛋白9B抗体 Q6EBV9 Mouse Unigene: 707300 Human Unigene: 716846 Human Unigene: 332252 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
自噬相关蛋白9B抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 **学 细胞凋亡
储存条件: Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid