葡萄糖转运蛋白5抗体
规格：1mg/1ml
英文名： GLUT5
别名： GLUT-5; GLUT 5; Glucose Transporter 5 GLUT5; Glucose Transporter 5 Facilitated glucose transporter member 5; Fructose transporter; Glucose transporter type 5 small intestine; SLC2A5; Solute carrier fa
分子量： 55kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GLUT5
交叉反应：Human, Mouse, Rat, Dog, Rabbit,
细胞定位：细胞膜
葡萄糖转运蛋白5抗体产品介绍：background: Ten types of glucose/fructose transport carrier proteins designated as Glut 1-10 facilitate glucose/fructose transport across the cell membrane. Molecular cloning of glucose transporters have identified a family of closely related genes that encodes at least 7 proteins exhibiting high degree of amino acid homology (45%-65%) all in the molecular weight range of 40-60 kDa. Individual members of the Glut family have predicted secondary structure characteristic of 12 membrane spanning domains of other transport carriers. Majority of the differences in sequence homology in Glut proteins occur at 4 hydrophilic domains that may play a role in distinct tissue-specific pattern of expression and targeting. All Glut proteins are glycosylated at or near the C-terminus and are present on either cell surface or in intracellular sites. Some transporters exhibit dynamic trafficking between intracellular storage sites and plasma membranes in response to various stimuli. In 葡萄糖转运蛋白5抗体some tissues Glut proteins are asymmetrically distributed between apical and basolateral membranes as in blood brain barrier and blood testis barriers. Glut 5 seems to function primarily as a fructose transporter; it is expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose Function: Cytochalasin B-sensitive carrier. Seems to function primarily as a fructose transporter. Subcellular葡萄糖转运蛋白5抗体 Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue. Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
葡萄糖转运蛋白5抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 信号转导 转录调节因子 转运蛋白 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid