突触结合蛋白5抗体
规格：1mg/1ml
英文名： Synaptotagmin 5
别名： Synaptotagmin 5; Synaptotagmin IX; Synaptotagmin V; Synaptotagmin-5; Syt5; SYT5_HUMAN; SytV.
分子量： 43kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Synaptot
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞浆 细胞膜
突触结合蛋白5抗体产品介绍：background: Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C (see MIM 176960) regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules (summary by Hudson and Birnbaum, 1995 [PubMed 7597049]).[supplied by OMIM, Feb 2011]. Function: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)-dependent secretion of norepinephrine in PC12 cells. Required for export突触结合蛋白5抗体 from the endocytic recycling compartment to the cell surface (By similarity). Subunit: Homodimer. Can also form heterodimers with SYT6. Interacts with both alpha- and beta-tubulin (By similarity). Subcellular Location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein (By similarity). Recycling endosome membrane; Single-pass membrane protein (By similarity). 突触结合蛋白5抗体Note=In mast cells, localizes to the endocytic recycling compartment (By similarity). Similarity: Belongs to the synaptotagmin family. Contains 2 C2 domains. Database links: UniProtKB/Swiss-Prot: O00445.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
突触结合蛋白5抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 神经生物学 信号转导 细胞类型标志物 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid