腺苷单磷酸活化蛋白激酶β2抗体
规格：1mg/1ml
英文名： AMPK beta 2
别名： AMP activated protein kinase beta 2 non catalytic subunit; AMPK beta 2; AMPK beta 2 chain; PRKAB 2; Protein kinase AMP activated beta 2 non catalytic subunit; AAKB2_HUMAN.
分子量： 30kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human AMPK bet
交叉反应：Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit,
细胞定位：
腺苷单磷酸活化蛋白激酶β2抗体产品介绍：background: PRKAB2 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status and plays a role in protecting cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase (ACC). It also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase (HMGCR) and hormone-sensitive lipase. PRKAB2 may be a positive regulator of AMPK activity. Function: AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. Also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA 腺苷单磷酸活化蛋白激酶β2抗体reductase and hormone-sensitive lipase. This is a regulatory subunit, may be a positive regulator of AMPK activity. It may also serve as an adapter molecule for the catalytic alpha-subunit. Post-translational modifications: Phosphorylated when associated with the catalytic subunit. Similarity: Belongs to the 5'-AMP-activated protein kinase beta subunit family. Gene ID: 5565 Database links: Entrez Gene:腺苷单磷酸活化蛋白激酶β2抗体 5565 Human Entrez Gene: 108097 Mouse Entrez Gene: 64562 Rat Omim: 602741 Human SwissProt: O43741 Human SwissProt: Q6PAM0 Mouse SwissProt: Q9QZH4 Rat Unigene: 50732 Human Unigene: 31175 Mouse Unigene: 207202 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
腺苷单磷酸活化蛋白激酶β2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 信号转导 细胞凋亡 转录调节因子 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid