转化因子样蛋白4抗体
规格：1mg/1ml
英文名： MLX
别名： BigMax protein; MAD7 antibody Max like bHLHZip protein; Max like protein X; MLXIP; MONDOA; MXD7; Protein Mlx; TCFL4; transcription factor like 4; Transcription factor like protein 4; MLX_HUMAN.
分子量： 33kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MLX
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：
转化因子样蛋白4抗体产品介绍：background: The product of this gene belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. These factors form heterodimers with Mad proteins and play a role in proliferation, determination and differentiation. This gene product may act to diversify Mad family function by its restricted association with a subset of the Mad family of transcriptional repressors, namely, Mad1 and Mad4. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]. Function: Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MAD1, MAD4, MNT, WBSCR14 and MLXIP which recognizes the core sequence 5'-CACGTG-3'. The TCFL4-MAD1, TCFL4-MAD4, TCFL4-WBSCR14 complexes are transcriptional repressors. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation. Subunit: 转化因子样蛋白4抗体Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAD1, MAD4, MNT, WBSCR14 and MLXIP. Can also bind DNA as a homodimer. Subcellular Location: Isoform Alpha: Cytoplasm. Note=Found predominantly in the cytoplasm. Isoform Beta: Cytoplasm. Note=Found predominantly in the cytoplasm. Isoform Gamma: Nucleus. Note=Found predominantly in the nucleus. Tissue Specificity: Expressed in all tissues tested, including spleen, thymus, prostate, ovary, intestine, colon, peripheral blood leukocyte, heart, liver, 转化因子样蛋白4抗体skeletal muscle and kidney. Lower levels of expression in testis, brain, placenta and lung. Similarity: Contains 1 basic helix-loop-helix (bHLH) domain. Database links: UniProtKB/Swiss-Prot: Q9UH92.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
转化因子样蛋白4抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid