G蛋白β1抗体/鸟嘌呤核苷酸结合蛋白β亚基1
规格：1mg/1ml
英文名： G protein beta 1
别名： Beta subunit signal transducing proteins GS/GI; G protein beta 1 subunit; GBB1; Guanine nucleotide binding protein beta 1 subunit; Transducin beta chain 1; GBB1_HUMAN.
分子量： 37kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human G protei
交叉反应：Human, Mouse, Rat, Chicken, Pig, Cow, Sheep,
细胞定位：
G蛋白β1抗体/鸟嘌呤核苷酸结合蛋白β亚基1产品介绍：background: Heterotrimeric guanine nucleotide binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. GNB1 is a beta subunit. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Function: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Subunit: G proteins are composed of 3 units, alpha, beta and gamma. Interacts with ARHGEF18 and RASD2. The heterodimer formed byG蛋白β1抗体/鸟嘌呤核苷酸结合蛋白β亚基1 GNB1 and GNG2 interacts with PTH1R (via C-terminus). Post-translational modifications: Phosphorylation at His-266 by NDKB contributes to G protein activation by increasing the high energetic phosphate transfer onto GDP (By similarity).G蛋白β1抗体/鸟嘌呤核苷酸结合蛋白β亚基1 Similarity: Belongs to the WD repeat G protein beta family. Contains 7 WD repeats. Database links: UniProtKB/Swiss-Prot: P62873.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
G蛋白β1抗体/鸟嘌呤核苷酸结合蛋白β亚基1产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 转录调节因子 结合蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid