长链脂肪酸辅酶A连接酶抗体
规格：1mg/1ml
英文名： SLC27A2
别名： ACSVL1; FACVL1; FATP 2; FATP2; Fatty acid coenzyme A ligase, very long chain 1; Fatty acid transport protein 2; hFACVL1; HsT17226; Long chain fatty acid CoA ligase; Solute carrier family 27 (fatty aci
分子量： 70kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SLC27A2/
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞浆 细胞膜
长链脂肪酸辅酶A连接酶抗体产品介绍：background: SLC27A2 is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long chain fatty acids into fatty acyl-CoA esters, and thereby may play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. Function: Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid 长链脂肪酸辅酶A连接酶抗体deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity). Subcellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Peroxisome长链脂肪酸辅酶A连接酶抗体 membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in liver, kidney, placenta and pancreas. Similarity: Belongs to the ATP-dependent AMP-binding enzyme family. Database links: UniProtKB/Swiss-Prot: O14975.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
长链脂肪酸辅酶A连接酶抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 发育生物学 信号转导 转录调节因子 转运蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid