白三烯A4水解酶抗体
规格：1mg/1ml
英文名： LTA4H
别名： Leukotriene A4 hydrolase LTA4; LTA4 hydrolase; LTA4H; LKHA4_HUMAN.
分子量： 69kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human LTA4H
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆
白三烯A4水解酶抗体产品介绍：background: Leukotrienes are a group of bioactive compounds which play important roles in immediate hyposensitivity reactions and inflammation. Leukotriene A4 hydrolase hydrolyzes an epoxide moiety of leukotriene A4 (LTA4) to form leukotriene B4 (LTB4). The enzyme also has some peptidase activity. Function: Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity. Subunit: Monomer. Subcellular Location: Cytoplasm.白三烯A4水解酶抗体 Tissue Specificity: Isoform 1 and isoform 2 are expressed in monocytes, lymphocytes, neutrophils, reticulocytes, platelets and fibroblasts. Post-translational modifications: Phosphorylation at Ser-416 inhibits enzymatic activity. Similarity: Belongs to the peptidase M1 family. Database links: Entrez Gene: 4048 Human Entrez Gene: 299732 Rat Omim: 151570 Human SwissProt: P09960 Human SwissProt: P30349 Rat Unigene: 白三烯A4水解酶抗体524648 Human Unigene: 104990 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 白三烯A4水解酶是一种含锌的金属蛋白酶，是水解白三烯A4（LTA4）产生白三烯B4的关键酶（LTB4），LTB4是参与炎症反应的主要物质。LTA4H还具有内在的氨基肽酶活性。 目前白三烯A4水解酶抗体LTA4H发挥氨基肽酶活性的底物和生理学功能尚不清楚。
产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid