过氧化还原酶1抗体
规格：1mg/1ml
英文名： PRDX1
别名： Peroxiredoxin-1; Peroxiredoxin 1; Prdx 1; Prdx1; PRDX1_HUMAN; Hbp23; Heme binding 23 kDa protein; Macrophage 23 Kd stress protein; Macrophage 23kDa stress protein; Macrophase stress protein 22kDa; Mac
分子量： 22kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PRDX1 (5
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,
细胞定位：细胞浆 细胞膜
过氧化还原酶1抗体产品介绍：background: This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jan 2011]. Function: Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates 过氧化还原酶1抗体the ability to GDPD5 to drive postmitotic motor neuron differentiation. Subunit: Homodimer; disulfide-linked, upon oxidation. May form heterodimers with AOP2. Interacts with GDPD5; forms a mixed-disulfide with GDPD5 (By similarity). Subcellular Location: Cytoplasm. Melanosome. Post-translational modifications: Phosphorylated on Thr-90 during the M-phase, which leads to a more than 80% decrease in enzymatic activity过氧化还原酶1抗体. Similarity: Belongs to the AhpC/TSA family. Contains 1 thioredoxin domain. Database links: Entrez Gene: 281997 Cow Entrez Gene: 5052 Human Entrez Gene: 18477 Mouse Entrez Gene: 117254 Rat Omim: 176763 Human SwissProt: Q9JKY1 Chinese Hamster SwissProt: Q06830 Human SwissProt: P35700 Mouse SwissProt: Q63716 Rat Unigene: 180909 Human Unigene: 30929 Mouse Unigene: 2845 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 该蛋白定位于细胞质。
过氧化还原酶1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid