肿瘤坏死因子配体超家族成员9抗体
规格:1mg/1ml
英文名: TNFSF9/CD137L
别名: 4 1BB L; 4 1BB ligand; 4 1BBL; Cd137l; Cd157l; homolog of mouse 4 1BB L; homolog of mouse 4 1BBL; ILA ligand (TNF related); Ly63l; receptor 4 1BB ligand; Tumor necrosis factor (ligand) superfamily mem
分子量: 25-27kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human TNFSF9
交叉反应:Human,
细胞定位:细胞膜
肿瘤坏死因子配体超家族成员9抗体产品介绍:background: This cytokine belongs to the tumour necrosis factor (TNF) ligand family. It is a ligand for TNFRSF9, which is a costimulatory molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process, and in the generation of cytotoxic T cells. This cytokine is also shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is found to be expressed in various carcinoma cell lines, and is thought to be involved in T cell-tumour cell interaction. Function: Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell 肿瘤坏死因子配体超家族成员9抗体death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. Subunit: Homotrimer. Subcellular Location: Membrane; Single-pass type II membrane protein. Tissue Specificity: Expressed in brain, placenta, lung, skeletal muscle and kidney. Similarity: Belongs to the tumor necrosis factor family. Gene ID: 8744 Database links: Entrez Gene: 8744 Human Omim: 肿瘤坏死因子配体超家族成员9抗体606182 Human SwissProt: P41273 Human Unigene: 1524 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肿瘤坏死因子配体超家族成员9抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 神经生物学 细胞表面分子 t-**细胞
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid