eIF4E结合蛋白2抗体
规格：1mg/1ml
英文名： eI4EBP2
别名： Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kin
分子量： 17/20kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：
**原：KLH conjugated synthetic peptide derived from human 4E-BP2
交叉反应：Human, Mouse, Rat, Cow,
eIF4E结合蛋白2抗体细胞定位：
产品介绍：background: This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. [provided by RefSeq, Oct 2008] Function: Regulates eIF4EeIF4E结合蛋白2抗体 activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase pathway. Subunit: Nonphosphorylated EIF4EBP2 interacts with EIF4E. Post-translational modifications: Phosphorylated on serine and threonine residues in response to insulin, EGF and PDGF. Similarity: Belongs to the eIF4E-binding eIF4E结合蛋白2抗体protein family. Gene ID: 1979 Database links: Entrez Gene: 1979 Human Entrez Gene: 13688 Mouse Entrez Gene: 361845 Rat Omim: 602224 Human SwissProt: Q13542 Human SwissProt: P70445 Mouse Unigene: 621200 Human Unigene: 730236 Human Unigene: 259516 Mouse Unigene: 24129 Rat
eIF4E结合蛋白2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 染色质和核信号 信号转导 细胞凋亡 转录调节因子
来源： Rabbit
外观： Lyophilized or Liquid