脂肪甘油三酯脂酶抗体
规格：1mg/1ml
英文名： Adipose Triglyceride Lipase
别名： PEDF R; Adipose Triglyceride Lipase; TTS 2.2; PEDFR; PEDF-R; ATGL; ATGL DESNUTRIN; Calcium independent phospholipase A2; Desnutrin; EC 3.1.1.3; IPLA2 zeta; PATATIN LIKE PHOSPHOLIPASE DOMAIN CONTAINING
分子量： 55kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
免疫原：KLH conjugated synthetic peptide derived from human ATGL
交叉反应：Human, Mouse, Rat,
细胞定位：细胞膜
脂肪甘油三酯脂酶抗体产品介绍：background: Adipose triglyceride lipase (ATGL) may function as a lipase and play a role in the adaptive response to a low energy state, such as fasting, by providing fatty acids to other tissues for oxidation. In addition, decreased expression of desnutrin in obesity models suggests its possible contribution to the pathophysiology of obesity. ATGL catalyzes the initial step in triglyceride hydrolysis in mammalian adipose tissue. ATGL contains a patatin domain common to plant acyl hydrolases. ATGL is highly expressed in adipose tissue of mice and humans. It exhibits high substrate specificity for triacylglycerol and is associated with lipid droplets. Inhibition of ATGL markedly decreases total adipose acyl hydrolase activity. Thus, ATGL and HSL coordinately catabolize stored triglycerides in adipose tissue of mammals. Subunit: Interacts with ABHD5; this association stimulates PNPLA2 triglyceride hydrolase activity. Subcellular Location: Lipid droplet. Cell membrane. 脂肪甘油三酯脂酶抗体Tissue Specificity: Highest expression in adipose tissue. Also detected in heart, skeletal muscle, and portions of the gastrointestinal tract. Detected in normal retina and retinoblastoma cells. Detected in retinal pigment epithelium and, at lower intensity, in the inner segments of photoreceptors and in the ganglion cell layer of the neural retina (at protein level). Similarity: Contains 1 patatin domain. Database links: Entrez Gene: 57104 Human Entrez Gene: 66853 Mouse Entrez Gene: 361676 Rat Omim: 609059 Human SwissProt: Q96AD5 Human SwissProt: Q8BJ56 Mouse 脂肪甘油三酯脂酶抗体SwissProt: P0C548 Rat Unigene: 654697 Human Unigene: 29998 Mouse Unigene: 19196 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Pathway: Glycerolipid metabolism; triacylglycerol degradation.
脂肪甘油三酯脂酶抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：免疫学 生长因子和** 糖尿病
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid