胚胎干细胞关键蛋白190抗体
规格：1mg/1ml
英文名： Oct-4B(OCT4B-190)NT
别名： Oct-4B; Oct4B; Oct 4B; Oct 4B-190; Oct4B-190; POU domain, class 5, transcription factor 1; Octamer-binding transcription factor 3; Oct-3; NF-A3; Otf-3; Otf3; POU5F1.
分子量： 21/39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human OCT4B-19
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow,
细胞定位：
胚胎干细胞关键蛋白190抗体产品介绍：background: This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG 胚胎干细胞关键蛋白190抗体(CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq]. Gene ID: 5460 Database links: Entrez Gene: 5460 Human Entrez Gene: 18999 Mouse Entrez Gene: 294562 Rat Omim: 164177 Human SwissProt: Q01860 Human SwissProt: P20263 Mouse Unigene: 249184 Human Unigene: 632482 Human Unigene: 646545 Human Unigene: 胚胎干细胞关键蛋白190抗体17031 Mouse Unigene: 161748 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. OCT4B-190蛋白能够增强细胞在应激条件下抵抗凋亡的能力。OCT4基因在干细胞的增殖、分化、应激反应、凋亡过程等多个生物学过程中发挥着重要的作用。
胚胎干细胞关键蛋白190抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 干细胞 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid