泛素载体蛋白R2抗体
规格:1mg/1ml
英文名: CDC34B
别名: CDC34B; E2 CDC34B; UBE2R2; Ubiquitin carrier protein R2; Ubiquitin conjugating enzyme E2 CDC34B; Ubiquitin conjugating enzyme E2 R2; Ubiquitin conjugating enzyme E2R 2; Ubiquitin conjugating enzyme UB
分子量: 26kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human CDC34B(1
交叉反应:Human, Mouse, Rat, Chicken, Horse, Rabbit,
细胞定位:
泛素载体蛋白R2抗体产品介绍:background: UBC3B is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. Function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes monoubiquitination and 'Lys-48'-linked polyubiquitination. May be involved in degradation of katenin.泛素载体蛋白R2抗体 Subunit: When phosphorylated, interacts with beta-TrCP (BTRC). Similarity: Belongs to the 泛素载体蛋白R2抗体ubiquitin-conjugating enzyme family. Database links: Entrez Gene: 54926 Human Entrez Gene: 67615 Mouse Entrez Gene: 299677 Rat Omim: 612506 Human SwissProt: Q712K3 Human SwissProt: Q6ZWZ2 Mouse Unigene: 643648 Human Unigene: 725177 Human Unigene: 389540 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产泛素载体蛋白R2抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 信号转导 转录调节因子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid