肌红蛋白抗体
规格：1mg/1ml
英文名： Myoglobin
别名： MB; MGC13548; Myoglobin; PVALB; MYG_HUMAN.
分子量： 17kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Myoglobi
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位：
肌红蛋白抗体产品介绍：background: Myoglobin is a small heme containing protein responsible for the oxygen deposition in muscle tissues. Only one form of myoglobin is expressed in cardiac and skeletal muscles. Myoglobin is known as a marker of myocardial damage and it has been used for more than three decades. Nowadays it still is very commonly used in clinical practice as an early marker of AMI. It appears in patient's blood 1 to 3 hours after onset of the symptoms, reaching peak level within 8 to 12 hours. Myoglobin is not so cardiac specific as cTnI or cTnT. Because of high myoglobin concentration in skeletal muscle tissue, even minor skeletal muscle injury results in the 肌红蛋白抗体significant increase of myoglobin concentration in blood. Thus myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis. Function: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. Similarity: Belongs to the globin family. Gene ID: 4151 Database links: Entrez Gene: 4151 Human Entrez Gene: 17189 Mouse Entrez Gene: 59108 Rat Omim:肌红蛋白抗体 160000 Human SwissProt: P02144 Human SwissProt: P04247 Mouse SwissProt: Q9QZ76 Rat Unigene: 517586 Human Unigene: 404074 Mouse Unigene: 40511 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 肌红蛋白存在于肌肉中，心肌中含量特别丰富，，有较高的组织特异性，肌红蛋白抗体是横纹肌的特异性标记物，但对肿瘤的敏感性较差。主要用于横纹肌肿瘤的诊断与鉴别诊断。少数恶性中胚叶混合瘤、睾丸畸胎瘤、肾母细胞瘤亦可见阳性表达。
产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid