丙酮酸脱氢酶激酶1抗体
规格：1mg/1ml
英文名： PDK1/Mitochondrial Pyruvate dehydrogenase kinase 1
别名： PDHK1; mitochondrial; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1; HGNC:8809; Mitochondrial pyruvate dehydrogenase kinase isoenzyme 1; PDK1; PDK 1; PDK-1; Pyruvate dehydrogenase kinase isofo
分子量： 45kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PDK1
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞浆 线粒体
丙酮酸脱氢酶激酶1抗体产品介绍：background: Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013] Function: Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit,丙酮酸脱氢酶激酶1抗体 thus contributing to the regulation of glucose metabolism. Subcellular Location: Mitochondrion matrix. Tissue Specificity: Expressed predominantly in the heart. Similarity: Belongs to the PDK/BCKDK protein kinase family. Contains 1 histidine kinase domain.丙酮酸脱氢酶激酶1抗体Gene ID: 5163 Database links: Entrez Gene: 5163 Human Entrez Gene: 228026 Mouse Entrez Gene: 116551 Rat Omim: 602524 Human SwissProt: Q15118 Human SwissProt: Q8BFP9 Mouse SwissProt: Q63065 Rat Unigene: 470633 Human Unigene: 34411 Mouse Unigene: 11185 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
丙酮酸脱氢酶激酶1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 生长因子和** 激酶和磷酸酶 合成与降解 糖蛋白 线粒体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid