发状分裂相关增强子-5抗体
规格：1mg/1ml
英文名： Hes5
别名： Hairy and enhancer of split 5; HES 5; HES5 protein; MGI:104876; HES5_HUMAN.
分子量： 18kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Hes5 (28
交叉反应：Human, Mouse, Rat, hu,mo,rat,chk,shp,dog,cow
细胞定位：细胞核
发状分裂相关增强子-5抗体产品介绍：background: This gene encodes a member of a family of basic helix-loop-helix transcriptional repressors. The protein product of this gene, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of this gene have been associated with developmental diseases and cancer.发状分裂相关增强子-5抗体 [provided by RefSeq, Dec 2008] Function: Transcriptional repressor of genes that require a bHLH protein for their transcription Subunit: Transcription repression requires formation of a complex with a corepressor protein of the Groucho/TLE family. Subcellular Location: Nucleus. Tissue Specificity: Expressed in fetal heart and brain tumors. Similarity: Contains 1 basic helix-loop-helix (bHLH) domain. Contains 1发状分裂相关增强子-5抗体 Orange domain. Gene ID: 388585 Database links: Entrez Gene: 388585 Human Entrez Gene: 15208 Mouse Entrez Gene: 79225 Rat SwissProt: Q5TA89 Human SwissProt: P70120 Mouse SwissProt: Q03062 Rat Unigene: 57971 Human Unigene: 137268 Mouse Unigene: 22422 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
发状分裂相关增强子-5抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 信号转导 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid