前列环素合成酶抗体
规格：1mg/1ml
英文名： CYP8A1
别名： CYP8; CYP8A1; Cytochrome P450, family 8, subfamily A, polypeptide 1; PGIS; Prostacyclin synthase; Prostaglandin I2 (prostacyclin) synthase; Prostaglandin I2 synthase; PTGI.
分子量： 55kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CYP8A1/P
交叉反应：Human, Mouse,
细胞定位：细胞浆 细胞膜
前列环素合成酶抗体产品介绍：background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane 前列环素合成酶抗体A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. Subcellular Location: Endoplasmic reticulum membrane; Single-pass membrane protein. Tissue Specificity: Widely expressed; particularly abundant in ovary, heart, skeletal muscle, lung and prostate. Similarity: Belongs to the cytochrome P450 family. Database links: Entrez Gene: 5740 Human Entrez Gene: 19223 Mouse Entrez 前列环素合成酶抗体Gene: 25527 Rat Omim: 601699 Human SwissProt: Q29626 Cow SwissProt: Q16647 Human SwissProt: O35074 Mouse SwissProt: Q62969 Rat Unigene: 5247 Cow Unigene: 302085 Human Unigene: 2339 Mouse Unigene: 73051 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
前列环素合成酶抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 **学 糖尿病 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid