R-钙粘附分子抗体
规格:1mg/1ml
英文名: R-cadherin
别名: Cadherin 4; Cadherin4; Cadherin-4 CDH4; R CAD; Retinal Cadherin.
分子量: 81kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human R-cadher
交叉反应:Human, Mouse, Rat, Chicken, Dog, Cow, Horse,
细胞定位:细胞膜
R-钙粘附分子抗体产品介绍:background: Cadherins constitute a superfamily of calcium-dependent intercellular adhesion molecules and are thought to play a role in cell recognition and segregation, morphogenetic regulation, and tumor suppression. R Cadherin is expressed mainly in the brain but is also found in other tissues. Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May play an important role in retinal development. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Tissue R-钙粘附分子抗体Specificity: Expressed mainly in brain but also found in other tissues. Similarity: Contains 5 cadherin domains. Database links: Entrez Gene: 1002 Human Entrez Gene: 12561 Mouse Entrez Gene: 114588 Rat Omim: 603006 Human SwissProt: P55283 Human SwissProt: P39038 Mouse SwissProt: Q80ZV4 Mouse SwissProt: Q63149 Rat Unigene: 473231 Human Unigene: 598638 Human Unigene: 184711 Mouse Unigene: 382094 Mouse R-钙粘附分子抗体Unigene: 392073 Mouse Unigene: 214089 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. R-钙粘附分子,是依赖钙离子的细胞间糖蛋白粘附分子的一种,主要是参与细胞间同源性粘附、调控和介导细胞间相互反应,在肿瘤的迁移、分化中起到一定的作用。在脑组织中表达外,其他组织中已有定位。
R-钙粘附分子抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 激酶和磷酸酶 细胞粘附分子 糖蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid