钾电压阀门通道混合器相关亚家族成员7抗体
规格：1mg/1ml
英文名： KCNA7
别名： HAK 6; HAK6; KCNA 7; KV1.7; Potassium voltage gated channel shaker related subfamily member 7; Potassium voltage gated channel subfamily A member 7; Voltage dependent potassium channel Kv1.7; Voltage
分子量： 50kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KCNA7
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Rabbit,
细胞定位：细胞膜
钾电压阀门通道混合器相关亚家族成员7抗体产品介绍：background: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. The gene is expressed preferentially in skeletal muscle, heart and kidney. 钾电压阀门通道混合器相关亚家族成员7抗体It is a candidate gene for inherited cardiac disorders. [provided by RefSeq, Jul 2008] Function: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient (By similarity). Subunit: Heterotetramer of potassium channel proteins. Subcellular Location: Membrane; 钾电压阀门通道混合器相关亚家族成员7抗体Multi-pass membrane protein. Tissue Specificity: Highly expressed in skeletal muscle, heart and kidney. Similarity: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.7/KCNA7 sub-subfamily. Gene ID: 3743 Database links: Entrez Gene: 3743 Human Entrez Gene: 16495 Mouse Entrez Gene: 365241 Rat Omim: 176268 Human SwissProt: Q96RP8 Human SwissProt: Q17ST2 Mouse Unigene: 306973 Human Unigene: 12955 Mouse Unigene: 218566 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
钾电压阀门通道混合器相关亚家族成员7抗体产品应用：WB=1:100-500 ELISA=1:2000-5000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 神经生物学 通道蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid