蛋白酪氨酸磷酸酶非受体型4抗体
规格:1mg/1ml
英文名: MEG1
别名: MEG; Protein tyrosine phosphatase MEG1; PTN4; PTPase MEG1; PTPN4; Tyrosine protein phosphatase non receptor type 4; PTN4_HUMAN.
分子量: 106kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PTPN4/ME
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep,
细胞定位:
蛋白酪氨酸磷酸酶非受体型4抗体产品介绍:background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation. 蛋白酪氨酸磷酸酶非受体型4抗体[provided by RefSeq, Jul 2008] Function: May act at junctions between the membrane and the cytoskeleton. Subcellular Location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Similarity: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily. Contains 1 FERM domain. Contains 1 PDZ (DHR) domain. Contains 1 tyrosine-protein phosphatase domain. Database links: Entrez Gene: 5775 Human Entrez Gene: 19258 Mouse Omim: 176878 Human SwissProt: P29074 Human SwissProt: Q8BQQ4 蛋白酪氨酸磷酸酶非受体型4抗体Mouse SwissProt: Q9WU22 Mouse Unigene: 469809 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
蛋白酪氨酸磷酸酶非受体型4抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 **学 信号转导 转录调节因子 激酶和磷酸酶
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid