阶段特异性胚胎表面抗原-3抗体
规格：1mg/1ml
英文名： SSEA3
别名： B3GT5_MOUSE; Beta-1,3-galactosyltransferase 5; Beta-1,3-GalTase 5; Beta3Gal-T5; Beta3GalT5; b3Gal-T5; Beta-3-Gx-T5 Stage-specific embryonic antigen 3 synthase; SSEA-3 synthase; UDP-Gal:beta-GlcNAc bet
分子量： 36kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：4-8 cell stage mouse embryos.
交叉反应：Mouse, Rat,
细胞定位：
阶段特异性胚胎表面抗原-3抗体产品介绍：background: SSEA3 is a globoseries carbohydrate antigen present on both cell surface glycolipids and glycopeptides. It is found on the surface of mouse oocytes, becoming restricted to the intracellular mass of the early blastocyst and then to the primitive endoderm. It is present on the surface of human teratocarcinoma cells (EC), embryonic germ cells (EG) and embryonic stem cells (ES) but not mouse undifferentiated mouse cells of these types. SSEA3 expression decreases as human EC, ES and EG cells differentiate but increases on differentiation of mouse EC, ES and EG cells. It is also found on the surface of mouse erythrocytes. Function: 阶段特异性胚胎表面抗原-3抗体Catalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure. Can use glycolipid LC3Cer as an efficient acceptor. Also catalyzes the transfer of Gal to the terminal GalNAc unit of the globoside GB4, thereby synthesizing the glycolipid GB5, also known as the stage-specific embryonic antigen-3 (SSEA-3). Subcellular Location: Golgi 阶段特异性胚胎表面抗原-3抗体apparatus membrane; Single-pass type II membrane protein (Potential). Tissue Specificity: Expressed in brain and kidney. Similarity: Belongs to the glycosyltransferase 31 family. Database links: UniProtKB/Swiss-Prot: Q9JI67.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
阶段特异性胚胎表面抗原-3抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 干细胞 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid