染色质结合蛋白Cbx8抗体
规格：1mg/1ml
英文名： Cbx8
别名： Chromobox protein homolog 8; HPC3; Pc3; Polycomb 3 homolog; RC1; Rectachrome 1; CBX8_HUMAN.
分子量： 43kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Cbx8
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核
染色质结合蛋白Cbx8抗体产品介绍：background: Cbx8, also known as Pc3, is a member of the Polycomb gene family and is required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. Cbx8 contains a chromodomain and is able to modify chromatin and histones. Function: Component of a Polycomb group (PcG) multiproteinPRC1-like complex, a complex class required to maintain thetranscriptionally repressive state of many genes, including Hoxgenes, throughout development. PcG PRC1 complex acts via chromatinremodeling and modification of histones; it mediatesmonoubiquitination of histone H2A 'Lys-119', rendering染色质结合蛋白Cbx8抗体 chromatinheritably changed in its expressibility. Subunit: Component of a PRC1-like complex. Interacts with RING1RNF2, PCGF1, PCGF2, PCGF3, BMI1, PCGF5 AND PCGF6. Interacts withMLLT3 and histone H3. Interacts with PHC2 (By similarity). Subcellular Location: Nucleus. Similarity: Contains 1 chromo domain. Gene ID: 57332 Database links: Entrez Gene: 506458 Cow Entrez Gene: 57332 Human 染色质结合蛋白Cbx8抗体Entrez Gene: 30951 Mouse Entrez Gene: 303731 Rat SwissProt: Q9HC52 Human SwissProt: Q9QXV1 Mouse Unigene: 387258 Human Unigene: 99953 Mouse Unigene: 43722 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
染色质结合蛋白Cbx8抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 信号转导 干细胞 转录调节因子 结合蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid