磷酸化磷酯酶Cβ3抗体
规格：1mg/1ml
英文名： Phospho-PLC beta3 (Ser537)
别名： PLC beta3 (Ser537); Phospholipase C beta 3; Phospholipase C beta 3 (phosphatidylinositol specific); PLC beta 3; PLCB3 antibody 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase beta 3; Phospho
分子量： 136kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated Synthesised phosphopeptide derived from human
交叉反应：Human, Mouse, Rat, Dog, Pig, Horse,
细胞定位：细胞膜
磷酸化磷酯酶Cβ3抗体产品介绍：background: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. 磷酸化磷酯酶Cβ3抗体Two transcript variants encoding different isoforms have been found for this gene. Function: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. Subunit: Interacts with SHANK2. Interacts with LPAR2. Subcellular Location: Membrane; Peripheral membrane protein. Similarity: Contains 1 C2 domain. Contains 1 PI-PLC X-box domain. Contains 1 PI-PLC Y-box domain. Gene ID: 5331 Database links: Entrez Gene: 5331 Human Entrez Gene: 磷酸化磷酯酶Cβ3抗体18797 Mouse Entrez Gene: 29322 Rat Omim: 600230 Human SwissProt: Q01970 Human SwissProt: P51432 Mouse SwissProt: Q99JE6 Rat Unigene: 523761 Human Unigene: 591953 Human Unigene: 273204 Mouse Unigene: 16983 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产磷酸化磷酯酶Cβ3抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 转录调节因子 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid