磷酸化心脏肌球蛋白轻链2抗体
规格：1mg/1ml
英文名： Phospho-MYL(Ser19)
别名： Cardiac myosin light chain-2; Cardiac ventricular myosin light chain 2; CMH10; MLC 2v; MLC2; MYL 2; Myosin light chain 2 regulatory cardiac slow; Myosin light polypeptide 2 regulatory cardiac slow; My
分子量： 18kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated Synthesised phosphopeptide derived from human
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆
磷酸化心脏肌球蛋白轻链2抗体产品介绍：background: Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008] Subunit: Myosin is a hexamer of 2 heavy chains and 4 light chains. Subcellular Location: Cytoplasm, myofibril, sarcomere, A band Post-translational modifications: N-terminus is methylated by METTL11A/NTM1. Phosphorylated by MYLK3. DISEASE: Defects in MYL2 are the cause of familial hypertrophic cardiomyopathy type 10 (CMH10) [MIM:608758]. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and 磷酸化心脏肌球蛋白轻链2抗体chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death. Similarity: Contains 3 EF-hand domains.磷酸化心脏肌球蛋白轻链2抗体 Gene ID: 4633 Database links: Entrez Gene: 4633 Human Entrez Gene: 17906 Mouse Entrez Gene: 363925 Rat Omim: 160781 Human SwissProt: P10916 Human SwissProt: P51667 Mouse SwissProt: P08733 Rat Unigene: 75535 Human Unigene: 1529 Mouse Unigene: 37176 Rat Unigene: 6534 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸化心脏肌球蛋白轻链2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid