磷酸化FRA-1蛋白抗体
规格:1mg/1ml
英文名: Phospho-FRA1 (Ser265)
别名: FOSL1; Fos related antigen 1; FOS L1; FOS like antigen 1; FOSL 1; FOSL1 protein; FRA 1; Fos-related antigen 1; FOSL1_HUMAN; FRA-1.
分子量: 28kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated Synthesised phosphopeptide derived from human
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位:
磷酸化FRA-1蛋白抗体产品介绍:background: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. 磷酸化FRA-1蛋白抗体[provided by RefSeq]. Subunit: Heterodimer. Subcellular Location: Nucleus. Similarity: Belongs to the bZIP family. Fos subfamily. Contains 1 bZIP (basic-leucine zipper) domain. Gene ID: 8061 Database links: Entrez Gene: 8061 Human Omim: 136515 Human磷酸化FRA-1蛋白抗体 SwissProt: P15407 Human Unigene: 283565 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. FOSL1蛋白对细胞因子、生长因子、感染或致癌刺激等生理或病理信号发生应答,调节基因的转录, 参与细胞的增殖、分化等过程。 FOSL1在肿瘤形成及发展过程中, 通过促进细胞增殖、抑制分化、促进肿瘤细胞的侵袭和转移等过程发挥作用。
磷酸化FRA-1蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:转录调节因子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid