磷酸化转录调节因子CEBP α 抗体
规格：1mg/1ml
英文名： Phospho-CEBP alpha (Ser21)
别名： Apoptotic cysteine protease; Apoptotic protease Mch 5; C/EBP alpha; CAP4; Caspase 8 precursor; CCAAT Enhancer Binding Protein alpha; CEBP; CEBP A; CEBP alpha; CEBPA; FADD homologous ICE/CED 3 like pro
分子量： 38kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated Synthesised phosphopeptide derived from human
交叉反应：Human, Mouse, Rat, Pig, Cow, Rabbit,
细胞定位：细胞核
磷酸化转录调节因子CEBP α 抗体产品介绍：background: The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells. Mutations in this gene are frequently found in acute myeloid leukemia (AML). Function:磷酸化转录调节因子CEBP α 抗体 C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Subunit: Interacts with PRDM16 (By similarity). Binds DNA as a dimer and can form stable heterodimers with C/EBP beta and gamma. Interacts with UBN1. Interacts with HBV protein X. Interacts with ZNF638; this interaction increases transcriptional activation. Subcellular Location: Nucleus. Similarity: Belongs to the bZIP family. C/EBP subfamily. Contains 1 bZIP domain. Gene 磷酸化转录调节因子CEBP α 抗体ID: 1050 Database links: Entrez Gene: 1050 Human Entrez Gene: 12606 Mouse Entrez Gene: 24252 Rat Omim: 116897 Human SwissProt: P49715 Human SwissProt: P53566 Mouse SwissProt: P05554 Rat Unigene: 76171 Human Unigene: 349667 Mouse Unigene: 153603 Rat Unigene: 204833 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸化转录调节因子CEBP α 抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 信号转导 细胞凋亡 转录调节因子 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid