γ谷氨酰转移酶抗体
规格:1mg/1ml
英文名: GGT1
别名: CD224; Gamma glutamyl transpeptidase; Gamma glutamyltransferase 1; Gamma glutamyltranspeptidase 1; Gamma-glutamyltransferase 1; Gamma-glutamyltranspeptidase 1 light chain; GGT 1; GGT; GGT1; GGT1_HUMAN
分子量: 61kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human GGT1
交叉反应:Human, Mouse, Rat,
细胞定位:细胞膜
γ谷氨酰转移酶抗体产品介绍:background: Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracelular GSH level. It is part of the cell antioxidant defense mechanism. Catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors. Alternatively, glutathione can be hydrolyzed to give Cys-Gly and gamma glutamate. Isoform 3 seems to be inactive. Tissue specificity: Detected in fetal and ***** kidney and liver, ***** pancreas, stomach, intestine, γ谷氨酰转移酶抗体placenta and lung. Isoform 3 is lung-specific. There are several other tissue-specific forms that arise from alternative promoter usage but that produce the same protein. Subunit: Heterodimer composed of the light and heavy chains. The active site is located in the light chain. Subcellular Location: Membrane; Single-pass type II membrane protein. Tissue Specificity: Detected in fetal and ***** kidney and liver,γ谷氨酰转移酶抗体 ***** pancreas, stomach, intestine, placenta and lung. Isoform 3 is lung-specific. There are several other tissue-specific forms that arise from alternative promoter usage but that produce the same protein. Similarity: Belongs to the gamma-glutamyltransferase family. Gene ID: 2678 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
γ谷氨酰转移酶抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-200 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid