乳腺珠蛋白1抗体
规格：1mg/1ml
英文名： Mammaglobin A
别名： Mammaglobin 1; Mammaglobin A; Mammaglobin-1; Mammaglobin-A; MGB 1; MGB1; Prostatein C3 subunit; prostatein peptide C3; Prostatic steroid binding protein, allele C3(1); SCGB2A2; Secretoglobin; Secretog
分子量： 9kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from rat Mammaglobi
交叉反应：Rat,
乳腺珠蛋白1抗体细胞定位：分泌型蛋白
产品介绍：background: Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement. Function: Part of prostatein which is the major secretory glycoprotein of ventral prostate gland.乳腺珠蛋白1抗体 Steroid-binding protein; can bind non-polar steroids, cholesterol and a group of small proline-rich peptides. Subunit: Prostatein is composed of three different peptides called C1, C2 and C3. These form covalent C1:C3 (F) and C2:C3 (S) heterodimers whose non-covalent association forms tetrameric (C1:C3/C3:C2) prostatein molecules. Subcellular Location: Secreted. Tissue Specificity: Highly expressed in ventral prostate. Similarity: Belongs to the secretoglobin family. Lipophilin subfamily. Gene ID: 361725 Database links: Entrez Gene: 4250 Human Entrez Gene: 100040203 乳腺珠蛋白1抗体Mouse Entrez Gene: 361725 Rat Omim: 605562 Human SwissProt: Q13296 Human Unigene: 46452 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 乳腺球蛋白是一个乳腺相关糖蛋白，它是一个分泌素家族（包括**球蛋白和lipophilin）成员的远亲。与其他分泌素家族成员不同，乳腺球蛋白的mRNA在乳腺组织中特异表达。在石蜡组织切片的检测中，该抗体检测乳腺癌组织中的乳腺珠蛋白敏感度高达80%。当和其他乳腺特异标记如GCDFP-15联合应用时，检测乳腺珠蛋白敏感度高达84%。有资料表明检测乳腺球蛋白，在鉴定原发癌是否发生转移中起到至关重要的作用。
乳腺珠蛋白1抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 结合蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid