肿瘤坏死因子受体超家族成员5抗体
规格：1mg/1ml
英文名： CD40L/TNFRSF5
别名： Tumor necrosis factor receptor superfamily , member 5; B cell associated molecule CD40; B cell surface antigen CD40; B cell-associated molecule; B-cell surface antigen CD40; Bp50; CD 40; CD40; CD40 an
分子量： 30kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CD40/TNF
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit,
细胞定位：细胞膜 分泌型蛋白
肿瘤坏死因子受体超家族成员5抗体产品介绍：background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two肿瘤坏死因子受体超家族成员5抗体 alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul2008]. Subcellular Location: Isoform I: Cell membrane; Single-pass type I membrane protein. Isoform II: Secreted. Tissue Specificity: B-cells and in primary carcinomas. Similarity: Contains 4 TNFR-Cys repeats. Database links: Entrez Gene: 959 Human Entrez 肿瘤坏死因子受体超家族成员5抗体Gene: 21947 Mouse Entrez Gene: 84349 Rat Omim: 300386 Human SwissProt: P29965 Human SwissProt: P27548 Mouse SwissProt: Q9Z2V2 Rat Unigene: 592244 Human Unigene: 4861 Mouse Unigene: 44218 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肿瘤坏死因子受体超家族成员5抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 **学 干细胞 细胞表面分子 **细胞 b-**细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid