辅肌动蛋白相关LIM蛋白抗体
规格:1mg/1ml
英文名: PDLIM3
别名: Actinin associated LIM protein; Actinin-associated LIM protein; Alpha actinin 2 associated LIM protein; Alpha-actinin-2-associated LIM protein; DKFZp686L0362; Enigma homolog; PDLI3_HUMAN; PDLIM 3; PDL
分子量: 39kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PDLIM3
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位:
辅肌动蛋白相关LIM蛋白抗体产品介绍:background: The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy. 辅肌动蛋白相关LIM蛋白抗体Function: May play a role in the organization of actin filament arrays within muscle cells. Subunit: Interacts with ACTN2. Subcellular Location: Cytoplasm, myofibril, sarcomere, Z line. Note=Localizes to myofiber Z-lines. Tissue Specificity: Isoform 1 is highly expressed in differentiated skeletal muscle. Isoform 2 is heart-specific. Similarity: Contains 1 LIM zinc-binding domain. Contains 1 PDZ (DHR) domain.辅肌动蛋白相关LIM蛋白抗体 Database links: UniProtKB/Swiss-Prot: Q53GG5.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
辅肌动蛋白相关LIM蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 信号转导 细胞骨架
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid