脂滴相关蛋白TIP47抗体
规格:1mg/1ml
英文名: TIP47/Perilipin 3
别名: TIP47; 47 kDa MPR binding protein; Cargo selection protein TIP47; M6PRBP 1; M6PRBP1; Mannose 6 phosphate receptor binding protein 1; MGC11117; MGC2012; MPR binding protein 47 kDa; Perilipin 3; Perilip
分子量: 48kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human TIP47
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
细胞定位:细胞浆 细胞膜
脂滴相关蛋白TIP47抗体产品介绍:background: Mannose 6-phosphate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. M6PRBP1 interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Subunit: Homooligomer. Interacts with M6PR (via the cytoplasmic domain). Interacts with IGF2R (via the cytoplasmic domain). Isoform 2 may 脂滴相关蛋白TIP47抗体exist as a homodimer (known as PP17C). Subcellular Location: Cytoplasm. Endosome membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Lipid droplet (Potential). Note=Membrane associated on endosomes. Detected in the envelope and the core of lipid bodies and in lipid sails. Similarity: Belongs to the perilipin family. Database links: Entrez Gene: 10226 Human Entrez Gene: 66905脂滴相关蛋白TIP47抗体 Mouse Entrez Gene: 316130 Rat Omim: 602702 Human SwissProt: O60664 Human SwissProt: Q9DBG5 Mouse Unigene: 140452 Human Unigene: 311696 Mouse Unigene: 9506 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
脂滴相关蛋白TIP47抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid