抑癌基因ras同源家族1抗体
规格：1mg/1ml
英文名： ARHI
别名： DIRA3; DIRAS family GTP binding RAS like 3; Distinct subgroup of the Ras family member 3; GTP binding protein Di Ras3; NOEY2; Rho related GTP binding protein RhoI; RHOI; DIRA3_HUMAN.
分子量： 25kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ARHI
交叉反应：Human,
细胞定位：
抑癌基因ras同源家族1抗体产品介绍：background: ARHI contains a highly conserved GTP-binding domain, a putative effector domain distinct from that of RAS and RAP proteins, and a C-terminal membrane localization motif. ARHI mRNA is detected in all normal breast and ovarian epithelial cell cultures tested, as well as in normal ovary, heart, liver, pancreas and brain however ARHI expression is down-regulated in breast and ovarian tumors. Reactivation of ARHI expression in breast cancer cells is associated with increased histone H3 acetylation 抑癌基因ras同源家族1抗体and decreased lysine 9 methylation of histone H3. Subcellular Location: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential). Tissue Specificity: Expressed in normal ovarian and breast epithelial cells but not in ovarian and breast cancers. Similarity: Belongs to the small GTPase superfamily. Di-Ras family. Gene ID: 9077 Database links: Entrez Gene: 9077 Human Omim: 抑癌基因ras同源家族1抗体605193 Human SwissProt: O95661 Human Unigene: 194695 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
抑癌基因ras同源家族1抗体研究领域：肿瘤 细胞生物 **学 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid