钾离子通道蛋白G蛋白4抗体
规格：1mg/1ml
英文名： KCNG4
别名： KCNG4; KV6.3; KV6.4; MGC129609; MGC4558; Voltage-gated potassium channel subunit Kv6.4; KCNG4_HUMAN .
分子量： 59kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KCNG4/KV
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞浆 细胞膜
钾离子通道蛋白G蛋白4抗体产品介绍：background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. KCNG4 is a member of the potassium channel, voltage-gated, subfamily G. This member functions as a modulatory subunit. The protein has strong expression in brain.Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. 钾离子通道蛋白G蛋白4抗体This member functions as a modulatory subunit. The gene has strong expression in brain. Multiple alternatively spliced variants have been found in normal and cancerous tissues. Function: Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values. Subunit: Heteromultimer with KCNB1, KCNC1 and KCNF1. Does not form homomultimers. Subcellular Location: Cell membrane. Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB1. Tissue Specificity: Highly expressed in brain, and at lower levels in liver, small intestine and colon. Similarity:钾离子通道蛋白G蛋白4抗体 Belongs to the potassium channel family. G (TC 1.A.1.2) subfamily. Kv6.4/KCNG4 sub-subfamily. Gene ID: 93107 Database links: Entrez Gene: 93107 Human Entrez Gene: 66733 Mouse Omim: 607603 Human SwissProt: Q8TDN1 Human SwissProt: Q80XM3 Mouse Unigene: 335877 Human Unigene: 560407 Human Unigene: 358699 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
钾离子通道蛋白G蛋白4抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid