紧密连接蛋白4抗体
规格:1mg/1ml
英文名: Claudin 4
别名: Claudin4; CLDN 4; CLDN4; Clostridium perfringens enterotoxin receptor; Clostridium perfringens enterotoxin receptor 1; CPE R; CPE receptor; CPER; CPETR 1; CPETR; CPETR1; hCPE R; WBSCR8; Williams Beure
分子量: 23kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human CLDN4
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞膜
紧密连接蛋白4抗体产品介绍:background: Claudin 1-8 proteins are a family of transmembrane proteins associated with tight junctions. Tight junctions are specialized regions of cell to cell contact made up of network of strands that act as a molecular gasket for preventing the leakage of ions, water etc. between cells. They are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Different tissues exhibit different Claudin composition. Subunit: Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Interacts 紧密连接蛋白4抗体with EPHA2; phosphorylates CLDN4 and may regulate tight junctions. Subcellular Location: Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the claudin family. Gene ID: 1364 Database links: Entrez Gene: 紧密连接蛋白4抗体1364 Human Entrez Gene: 12740 Mouse Omim: 602909 Human SwissProt: O14493 Human SwissProt: O35054 Mouse Unigene: 647036 Human Unigene: 699253 Human Unigene: 7339 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产紧密连接蛋白4抗体品应用:WB=1:100-500 ELISA=1:2000-5000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:10-200 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid