尿皮质素UCN3抗体
规格:1mg/1ml
英文名: Urocortin 3
别名: SCP; SPC; Stresscopin; Ucn III; UCN3; UCN3 urocortin 3 stresscopin; UCNIII; Urocortin 3 stresscopin; Urocortin III; UCN3_HUMAN.
分子量: 4.6kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human UCN3
交叉反应:Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,
细胞定位:分泌型蛋白
尿皮质素UCN3抗体产品介绍:background: Urocortin 3 is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. A powerful cytoprotective effect of urocortin peptide administration against ischemia and reperfusion injury has been demonstrated in isolated cardiomyocyte models, as well as in the intact heart both in vitro and in vivo. Function: Urocortin 3 is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) 尿皮质素UCN3抗体gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. A powerful cytoprotective effect of urocortin peptide administration against ischemia and reperfusion injury has been demonstrated in isolated cardiomyocyte models, as well as in the intact heart both in vitro and in vivo. Subunit: Binds with high affinity to CRF receptors 2-alpha and 2-beta. Subcellular尿皮质素UCN3抗体Location: Secreted Similarity: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family. Gene ID: 114131 Database links: Entrez Gene: 114131 Human Omim: 605901 Human SwissProt: Q969E3 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
尿皮质素UCN3抗体产品应用:WB= ELISA= IHC-P= IHC-F= IF= (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 心血管 细胞生物 神经生物学 生长因子和** ***病
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid