肺Kruppel样因子抗体
规格:1mg/1ml
英文名: KLF2
别名: Kruppel like factor 2; Kruppel like factor; Kruppel like factor LKLF; Kruppel-like factor 2 (lung); Lung krueppel like factor; Lung Kruppel like zinc finger transcription factor; KLF 2; Klf2; KLF2_HUM
分子量: 39kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human KLF2
交叉反应:Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞核
肺Kruppel样因子抗体产品介绍:background: Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1; MIM 601974) and the selectin CD62L (SELL; MIM 153240) (summary by Weinreich et al., 2009 [PubMed 19592277]).[supplied by OMIM, Feb 2011] Function: Binds to the CACCC box in the beta-globin gene promoter and activates transcription . Subunit: Interacts with WWP1. Subcellular Location: Nucleus. 肺Kruppel样因子抗体Post-translational modifications: Ubiquitinated. Polyubiquitination involves WWP1 and leads to proteasomal degradation of this protein. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 3 C2H2-type zinc fingers. Gene ID: 10365 Database links: Entrez Gene: 10365 Human Entrez Gene: 16598 Mouse Entrez Gene: 306330 Rat Omim: 602016 Human SwissProt: Q9Y5W3 Human SwissProt: 肺Kruppel样因子抗体Q60843 Mouse SwissProt: Q9ET58 Rat Unigene: 107740 Human Unigene: 726356 Human Unigene: 26938 Mouse Unigene: 92653 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肺Kruppel样因子抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 转录调节因子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid