谷胱甘肽硫转移酶pi基因/Glutathione S Transferase pi抗体
规格：1mg/1ml
英文名： GSTP1
别名： Glutathione S-Transferase pi; GST-Pi; DFN7; Gst-P1; FAEES3; Fatty Acid Ethyl Ester Synthase III; Glutathione S Transferase Pi; GST3; GSTP1; GST pi; PI; GSTP1_HUMAN.
分子量： 23kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GstP1
交叉反应：Human, Mouse, Rat,
细胞定位：
谷胱甘肽硫转移酶pi基因/Glutathione S Transferase pi抗体产品介绍：background: Glutathione S-transferases (GSTs) function in the metabolic detoxification of various environmental carcinogens and lipid hydroperoxides. Members of the murine GSTP (glutathione S-transferase pi) family, termed Gstp1 and Gstp2, are linked to drug resistance and are markers for many cancers. Gstp proteins modulate cell signaling by interacting with c-Jun N-terminal kinase (JNK), and may play a protective role in the development of spontaneous tumors.谷胱甘肽硫转移酶pi基因/Glutathione S Transferase pi抗体 Gstp has been found in substantia nigra and may be associated with reactive oxygen species-induced neurological disorders such as Parkinson’s disease and may additionally protect against endothelial dysfunction induced by tobacco smoke exposure. Function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Subunit: Homodimer. Tissue Specificity: Ubiquitously expressed. Similarity: Belongs to the GST superfamily. Pi family. Contains 1 GST C-terminal domain. Contains 1 GST N-terminal domain. Gene ID: 2950 Database links: Entrez Gene: 2950 Human Omim: 134660 Human SwissProt: P09211谷胱甘肽硫转移酶pi基因/Glutathione S Transferase pi抗体 Human Unigene: 523836 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. GST-Pi是GST家族中的一种主要的同工酶，广泛存在于全身器官中，尤以肝肾含量高，具有**功能。在多种肿瘤中高表达。目前认为是肿瘤细胞产生耐药的一种标记，与肿瘤的耐药（阿霉素、顺铂、氮芥、环磷酰胺和瘤可宁等）有关。该抗体主要用于细胞耐**面的研究。
谷胱甘肽硫转移酶pi基因/Glutathione S Transferase pi抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:50-400 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 神经生物学 转录调节因子 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid