肥大细胞蛋白酶7样蛋白抗体
规格：1mg/1ml
英文名： Mast Cell Tryptase
别名： Tryptase delta; Delta-tryptase; HmMCP-3-like tryptase III; Mast cell mMCP-7-like; Tryptase-3; TPSD1; MCP7L1; MMCP-7L; MCP7-LIKE; EC 3.4.21.59; MGC95428; TRYD; Tryptase3; alpha II; EC 3.4.21.59; Lung t
分子量： 23kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TPSD1
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,
细胞定位：分泌型蛋白
肥大细胞蛋白酶7样蛋白抗体产品介绍：background: Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes.肥大细胞蛋白酶7样蛋白抗体 Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. This gene was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein. [provided by RefSeq, Jul 2008] Function: Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. Subunit: Homotetramer. Subcellular Location: Secreted. Note=Released from the secretory granules upon mast cell activation. Tissue Specificity: Expressed in colon, lung, heart and synovial tissue. May be specific to mast cells. Similarity: Belongs to the peptidase S1 family.肥大细胞蛋白酶7样蛋白抗体 Tryptase subfamily. Contains 1 peptidase S1 domain. Gene ID: 23430 7177 Database links: Entrez Gene: 7177 Human Entrez Gene: 100503895 Mouse Entrez Gene: 54271 Rat Omim: 191080 Human SwissProt: Q15661 Human SwissProt: Q02844 Mouse SwissProt: P27435 Rat Unigene: 405479 Human Unigene: 3301 Mouse Unigene: 10699 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肥大细胞蛋白酶7样蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid