髓系细胞触发受体样转录因子1抗体
规格:1mg/1ml
英文名: TREML1
别名: dJ238O23.3; GLTL1825; MGC119173; PRO3438; TLT 1; TLT1; TREM like transcript 1; Trem like transcript 1 protein; TREML 1; Triggering receptor expressed on myeloid cells like 1; Triggering receptor expre
分子量: 33kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human TREML1
交叉反应:Human, Mouse, Rat,
细胞定位:细胞浆 细胞膜 细胞外基质
髓系细胞触发受体样转录因子1抗体产品介绍:background: This gene encodes a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. The encoded protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants [provided by RefSeq, Nov 2012] Subunit: When phosphorylated, 髓系细胞触发受体样转录因子1抗体interacts with PTPN6. When phosphorylated, interacts with PTPN11. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Cytoplasm. Note=Sequestered in cytoplasmic vesicles in resting platelets. Transported to the cell surface after stimulation by thrombin. Soluble fragments can be released into the serum by proteolysis. Tissue Specificity: Detected in platelets, monocytic leukemia and in T-cell leukemia. Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain. Gene ID: 340205 Database links: Entrez Gene: 340205 Human Omim:髓系细胞触发受体样转录因子1抗体 609714 Human SwissProt: Q86YW5 Human Unigene: 117331 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
髓系细胞触发受体样转录因子1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:**学 **细胞 t-**细胞 b-**细胞
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid