唾液酸结合性**球蛋白样凝集素5抗体
规格：1mg/1ml
英文名： CD170
别名： SIGLEC5; CD170 antigen; CD33 antigen-like 2; CD33L2; mSiglec-F;OB-binding protein 2; OB-BP2; OBBP2; Obesity-binding protein 2; Sialic acid binding Ig-like lectin 5; Sialic acid binding immunoglobulin-
分子量： 59kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CD170
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,
细胞定位：细胞膜
唾液酸结合性**球蛋白样凝集素5抗体产品介绍：background: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha2,3-linked and alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. This molecule is expressed by monocytic/myeloid lineage cells. Found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. Expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differenciation. Function: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity:唾液酸结合性**球蛋白样凝集素5抗体 Expressed by monocytic/myeloid lineage cells. Found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. Expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation. Similarity: Belongs to the immunoglobulin superfamily.唾液酸结合性**球蛋白样凝集素5抗体 SIGLEC (sialic acid binding Ig-like lectin) family. Contains 2 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 Ig-like V-type (immunoglobulin-like) domain. Gene ID: 8778 Database links: Entrez Gene: 8778 Human Entrez Gene: 233186 Mouse Omim: 604200 Human SwissProt: O15389 Human SwissProt: Q920G3 Mouse Unigene: 310333 Human Unigene: 290569 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
唾液酸结合性**球蛋白样凝集素5抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 细胞粘附分子 细胞表面分子 细胞类型标志物 骨髓细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid