SLAMF6抗体
规格：1mg/1ml
英文名： SLAMF6/LY108
别名： LY108; Activating NK receptor; KALI; KALIb; MGC104953; NK T B antigen; NTB A; NTBA; SF2000; SLAM family member 6; SLAM family member 6 precursor; SLAMF6; SLAF6_HUMAN; NK-T-B-antigen; NTB-A; CD352.
分子量： 37kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from mouse SLAMF6
交叉反应：Mouse, Rat,
细胞定位：细胞膜
SLAMF6抗体产品介绍：background: SLAMF6 is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. It may play a role in the regulation of autoimmune diseases. Function: Triggers cytolytic activity only in natural killer cells (NK) SLAMF6抗体expressing high surface densities of natural cytotoxicity receptors. Subunit: Homodimer. Interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. Subcellular Location: Cell membrane; Single-pass type I membrane protein (Probable). Tissue Specificity: Expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. Similarity: Contains 1 Ig-like (immunoglobulin-like) domain. Gene ID:SLAMF6抗体 30925 Database links: Entrez Gene: 114836 Human Entrez Gene: 30925 Mouse Omim: 606446 Human SwissProt: Q96DU3 Human SwissProt: Q9ET39 Mouse Unigene: 492348 Human Unigene: 486404 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
SLAMF6抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 细胞表面分子 细胞类型标志物 自然杀伤细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid