细胞毒性受体NK-p80抗体
规格:1mg/1ml
英文名: NKp80
别名: C type lectin domain family 5 member C; CLEC5C; killer cell lectin like receptor F1; Killer cell lectin like receptor subfamily F member 1; KLRF 1; Lectin like receptor F1; MGC119907; MGC119908; MGC11
分子量: 27kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human KLRF1
交叉反应:Human,
细胞定位:细胞膜
细胞毒性受体NK-p80抗体产品介绍:background: KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009 [PubMed 18922855]).[supplied by OMIM, Oct 2009] Function: Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts. Subunit: Homodimer. Subcellular Location: Membrane; Single-pass type II membrane protein (Potential). Tissue Specificity: Strongly expressed in peripheral blood leukocytes and spleen, with weaker expression in lymph node and ***** liver, and no expression detected in bone marrow, thymus, and fetal liver. Not细胞毒性受体NK-p80抗体 expressed in brain, heart, placenta, lung, kidney, skeletal muscle, and pancreas. Within peripheral blood leukocyte and immunocyte cell lines, expression was predominant in NK cells but was also detected in monocytes. Similarity: Contains 1 C-type lectin 细胞毒性受体NK-p80抗体domain. Gene ID: 51348 Database links: Entrez Gene: 51348 Human Omim: 605029 Human SwissProt: Q9NZS2 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞毒性受体NK-p80抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:**学 自然杀伤细胞
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid