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巨噬细胞甘露糖受体CD206抗体

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产品名称: 巨噬细胞甘露糖受体CD206抗体
产品型号: Macrophage mannose receptor 1
产品展商: 单克隆抗体/多克隆抗体
产品文档: 无相关文档

简单介绍

巨噬细胞甘露糖受体CD206抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。巨噬细胞甘露糖受体CD206抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产品质量,质量稳定,实验效果明显。


巨噬细胞甘露糖受体CD206抗体  的详细介绍

巨噬细胞甘露糖受体CD206抗体

规格:1mg/1ml

英文名: Macrophage mannose receptor 1

别名: Mannose Receptor; Macrophage mannose receptor 1; C-type lectin domain family 13 member D; CD 206; CD206; CD206 antigen; CLEC13D; CLEC13DL; Macrophage mannose receptor 1; Macrophage mannose receptor; M

分子量: 160kDa

储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型:Polyclonal

亚型:IgG

纯化方法:affinity purified by Protein A

**原:KLH conjugated synthetic peptide derived from human CLEC13D

交叉反应:Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, Sheep,

细胞定位:细胞膜

巨噬细胞甘露糖受体CD206抗体产品介绍:background: The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. This gene is in close proximity to MRC1L1. The gene loci including this gene, MRC1L1, as well as LOC340843 and LOC340893, consist of two nearly identical, tandemly linked genomic regions, which are thought to be a part of a duplicated region. [provided by RefSeq].巨噬细胞甘露糖受体CD206抗体 Function: Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens. Subcellular Location: Endosome membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein. Similarity: Contains 8 C-type lectin domains. Contains 1 fibronectin type-II domain. [SIMILARITY] Contains 1 ricin B-type lectin domain. Gene ID: 4360 Database links: Entrez Gene: 4360 Human Entrez Gene: 17533 Mouse 巨噬细胞甘露糖受体CD206抗体Entrez Gene: 291327 Rat Omim: 153618 Human SwissProt: P22897 Human SwissProt: Q61830 Mouse Unigene: 75182 Human Unigene: 2019 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 巨噬细胞甘露糖受体,主要存在于巨噬细胞膜表面的模式识别受体,能够特异性识别甘露糖、岩藻糖或N-乙酰葡糖胺,介导巨噬细胞吞噬抗原,启动**反应.

巨噬细胞甘露糖受体CD206抗体产品应用:IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域:肿瘤  细胞生物  **学  转录调节因子  细胞膜受体  糖蛋白  

储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源: Rabbit

外观: Lyophilized or Liquid


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