MD-2蛋白抗体
规格：1mg/1ml
英文名： MD2
别名： ESOP 1; ESOP-1; ESOP1; LY 96; Ly-96; LY96; LY-96; LY96_HUMAN; Lymphocyte antigen 96; Lymphocyte antigen 96; MD 2; MD-2; md 2; MD 2 protein; MD2 protein; Myeloid differentiation protein 2; Protein MD 2
分子量： 16kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human LY-96
交叉反应：Human, Mouse, Rat, Cow, Horse, Rabbit,
MD-2蛋白抗体细胞定位：细胞外基质 分泌型蛋白
产品介绍：background: MD2 cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS. Function: Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria.MD-2蛋白抗体 Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS. Subunit: Heterogeneous homopolymer formed from homodimers; disulfide-linked. Belongs to the lipopolysaccharide (LPS) receptor, a multi-protein complex containing at least CD14, LY96 and TLR4. Binds to the extracellular domains of TLR2 and TLR4. Ligand binding induces interaction with TLR4 and oligomerization of the complex. Subcellular Location: Secreted, extracellular space. Post-translational modifications: N-glycosylated; high-mannose.MD-2蛋白抗体 Gene ID: 23643 Database links: Entrez Gene: 23643 Human Entrez Gene: 17087 Mouse Entrez Gene: 448830 Rat Omim: 605243 Human SwissProt: Q9Y6Y9 Human SwissProt: Q9JHF9 Mouse Unigene: 726603 Human Unigene: 116844 Mouse Unigene: 141496 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产MD-2蛋白抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid