MD-1蛋白抗体
规格：1mg/1ml
英文名： MD1
别名： BPAD; dJ80N2.1; LY86; LY-86; LY 86; Lymphocyte antigen 86; Lymphocyte antigen 86 precursor; Major affective disorder 1; MD-1; MD1; MD 1; MD1 protein; MD1 RP105 associated; MD1 RP105 associated; MMD-1;
分子量： 16kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human LY-86
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
细胞定位：
MD-1蛋白抗体产品介绍：background: MD1 is a 28 kDa molecule that is associated at the cell surface with RP105 (CD180). RP105 is a leucine-rich repeat (LRR) molecule that is expressed on B lymphocytes. It was first identified by a mAb that protects spleen B cells from irradiation-induced apoptosis. LRR proteins, such as Toll receptors, have a role in innate immunity. MD1 is primarily expressed by B cells, dendritic cells and monocytes, and promotes the recognition of, and subsequent signaling by LPS in the innate immune system. MD1 does not have any homology to other molecules. MD1 when expressed alone behaves as a secretory protein. Expression of MD1 in a cell increases the expression of RP105. Function: May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine MD-1蛋白抗体production. Important for efficient CD180 cell surface expression. Subcellular Location: Secreted. extracellular space. Associated with CD180 at the cell surface. Tissue Specificity: Highly expressed in B-cells, monocytes and tonsil. Gene ID: 9450 Database links: Entrez Gene: 9450 Human Entrez Gene: 17084 Mouse Entrez Gene: 396639 Pig Entrez Gene: 291359 Rat Omim: 605241 Human SwissProt: O95711 Human SwissProt: MD-1蛋白抗体O88188 Mouse Unigene: 653138 Human Unigene: 2639 Mouse Unigene: 3176 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MD-1蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid