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MD-1蛋白抗体

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产品名称: MD-1蛋白抗体
产品型号: MD1
产品展商: 单克隆抗体/多克隆抗体
产品文档: 无相关文档

简单介绍

MD-1蛋白抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。MD-1蛋白抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产品质量,质量稳定,实验效果明显。


MD-1蛋白抗体  的详细介绍

MD-1蛋白抗体

规格:1mg/1ml

英文名: MD1

别名: BPAD; dJ80N2.1; LY86; LY-86; LY 86; Lymphocyte antigen 86; Lymphocyte antigen 86 precursor; Major affective disorder 1; MD-1; MD1; MD 1; MD1 protein; MD1 RP105 associated; MD1 RP105 associated; MMD-1;

分子量: 16kDa

储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型:Polyclonal

亚型:IgG

纯化方法:affinity purified by Protein A

**原:KLH conjugated synthetic peptide derived from human LY-86

交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,

细胞定位:

MD-1蛋白抗体产品介绍:background: MD1 is a 28 kDa molecule that is associated at the cell surface with RP105 (CD180). RP105 is a leucine-rich repeat (LRR) molecule that is expressed on B lymphocytes. It was first identified by a mAb that protects spleen B cells from irradiation-induced apoptosis. LRR proteins, such as Toll receptors, have a role in innate immunity. MD1 is primarily expressed by B cells, dendritic cells and monocytes, and promotes the recognition of, and subsequent signaling by LPS in the innate immune system. MD1 does not have any homology to other molecules. MD1 when expressed alone behaves as a secretory protein. Expression of MD1 in a cell increases the expression of RP105. Function: May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine MD-1蛋白抗体production. Important for efficient CD180 cell surface expression. Subcellular Location: Secreted. extracellular space. Associated with CD180 at the cell surface. Tissue Specificity: Highly expressed in B-cells, monocytes and tonsil. Gene ID: 9450 Database links: Entrez Gene: 9450 Human Entrez Gene: 17084 Mouse Entrez Gene: 396639 Pig Entrez Gene: 291359 Rat Omim: 605241 Human SwissProt: O95711 Human SwissProt: MD-1蛋白抗体O88188 Mouse Unigene: 653138 Human Unigene: 2639 Mouse Unigene: 3176 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

MD-1蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域:**学  

储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源: Rabbit

外观: Lyophilized or Liquid


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