巨噬细胞清道夫受体抗体
规格:1mg/1ml
英文名: MARCO
别名: Macrophage receptor MARCO; Marco; MARCO_HUMAN; Macrophage receptor with collagenous structure; SCARA2; Scavenger receptor class A member 2.
分子量: 53kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human MARCO
交叉反应:Human, Mouse, Rat, Chicken, Dog, Guinea Pig, ,G
细胞定位:细胞膜
巨噬细胞清道夫受体抗体产品介绍:background: The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq]. Function: Pattern recognition receptor (PRR). Binds Gram-positive and 巨噬细胞清道夫受体抗体Gram-negative bacteria. Subunit: Homotrimer. Trimers may assemble in larger oligomers thus resulting in the creation of a large surface capable of interacting with very large ligands. Subcellular Location: Membrane; Single-pass type II membrane protein. Similarity: Contains 1 collagen-like domain. Contains 1 SRCR domain. Gene ID: 8685 Database links: Entrez Gene: 8685 Human Omim: 604870 Human SwissProt:巨噬细胞清道夫受体抗体 Q9UEW3 Human Unigene: 67726 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
巨噬细胞清道夫受体抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:50-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 微生物学 **及病毒
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid