**细胞活化基因-3抗体
规格:1mg/1ml
英文名: LAG-3
别名: Lymphocyte activation gene 3; CD223; FDC protein; LAG 3; LAG3; Lymphocyte activation gene 3 protein; LAG3_HUMAN.
分子量: 58kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human LAG-3 C-
交叉反应:Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,
细胞定位:细胞膜
**细胞活化基因-3抗体产品介绍:background: Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4. Function: Involved in lymphocyte activation. Binds to HLA class-II antigens (By similarity). **细胞活化基因-3抗体Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: On cell surface of activated NK and T-lymphocytes. Similarity: Contains 3 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 Ig-like V-type (immunoglobulin-like) domain. Gene ID: 3902 Database links: UniProtKB/Swiss-Prot: P18627.5 Entrez Gene: 3902 Human Omim: 153337 Human SwissProt: P18627 Human Unigene:**细胞活化基因-3抗体 409523 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
**细胞活化基因-3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 细胞类型标志物 自然杀伤细胞 t-**细胞
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid