前列腺素E合成酶2抗体
规格：1mg/1ml
英文名： PTGES2
别名： C9orf15; FLJ14038; Gamma interferon activated transcriptional element binding factor 1; GATE binding factor 1; GBF 1; GBF1; Membrane associated prostaglandin E synthase 2; MGC11289; Microsomal prostag
分子量： 43kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from mouse PTGES2
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow,
细胞定位：细胞核 细胞浆 细胞膜
前列腺素E合成酶2抗体产品介绍：background: The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene. [provided by RefSeq]. Function: Isomerase that catalyzes the conversion of unstable intermediate of prostaglandin E2 H2 (PGH2) into the more stable prostaglandin E2 (PGE2) form (By similarity). May also have transactivation activity toward IFN-gamma (IFNG), possibly via an interaction with CEBPB; however, the relevance of transcription activation activity remains unclear. Subunit: Homodimer. May interact with CEBPB. Subcellular Location: Golgi apparatus membrane; Single-pass membrane protein. Nucleus. Note=According to PubMed:12050152, some fraction may be nuclear. Prostaglandin E synthase 前列腺素E合成酶2抗体2 truncated form: Cytoplasm. Note=Synthetized as a Golgi membrane-bound protein, which is further cleaved into the predominant soluble truncated form. Tissue Specificity: Widely expressed. Expressed in brain, heart, liver, colon and lung. Similarity: Belongs 前列腺素E合成酶2抗体to the GST superfamily. Contains 1 glutaredoxin domain. Contains 1 GST C-terminal domain. Gene ID: 96979 Database links: Entrez Gene: 493639 Cow Entrez Gene: 80142 Human Entrez Gene: 96979 Mouse Entrez Gene: 311865 Rat Entrez Gene: 100294563 Sheep Omim: 608152 Human SwissProt: Q66LN0 Cow SwissProt: Q9H7Z7 Human SwissProt: Q8BWM0 Mouse Unigene: 495219 Human Unigene: 28048 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
前列腺素E合成酶2抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid