细胞表面**球蛋白样转录因子2抗体
规格：1mg/1ml
英文名： LILRB1
别名： LILRB1; Leukocyte immunoglobulin-like receptor subfamily B member 1; Leukocyte immunoglobulin-like receptor 1; LIR-1; Immunoglobulin-like transcript 2; Monocyte/macrophage immunoglobulin-like receptor
分子量： 72kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ILT2 (15
交叉反应：Human,
细胞定位：细胞膜
细胞表面**球蛋白样转录因子2抗体产品介绍：background: Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. Engagement of LILRB1 present on natural killer cells or T-cells by class I MHC molecules protects the target cells from lysis. Interaction with HLA-B or HLA-E leads to inhibition of the signal triggered by FCER1A and inhibits serotonin release. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions. Subunit: Binds 细胞表面**球蛋白样转录因子2抗体PTPN6 when phosphorylated. Binds FCGR1A. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Expressed on monocytes and B-cells, and at lower levels on dendritic cells. Detected at low levels in natural killer (NK) cells. Similarity: Contains 4 Ig-like C2-type (immunoglobulin-like) domains. Gene ID: 10859 Database links: Entrez Gene: 10859 Human Omim: 细胞表面**球蛋白样转录因子2抗体604811 Human SwissProt: Q8NHL6 Human Unigene: 667388 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞表面**球蛋白样转录因子2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-300 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 细胞膜受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid